SCHEMBL8056038

SCHEMBL8056038

Cc1ccccc1P(Cc1ccccc1-c1ccccc1CP(c1ccccc1)c1ccccc1)c1ccccc1C

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 1/20 0.32
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
HTR7 P34969 2/20 0.31
FFAR1 O14842 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9016327 0.91 TAAR1 (0.36) CTBP2PDCD1CD274TAAR1HTR7
SCHEMBL8029937 0.88 FFAR1 (0.38) PDCD1CD274TAAR1HTR7FFAR1
SCHEMBL720169 0.84 CYP3A4 (0.38) PDCD1CD274
SCHEMBL29695439 0.82 CYP3A4 (0.36) PDCD1CD274
Potassium SCHEMBL30843013 0.82 CYP3A4 (0.36) PDCD1CD274
Lithium SCHEMBL29695298 0.82 CYP3A4 (0.36) PDCD1CD274
Phosphine SCHEMBL29173742 0.82 CYP3A4 (0.36) PDCD1CD274
Bromide SCHEMBL30945893 0.80 CYP3A4 (0.35) PDCD1CD274
SCHEMBL6678983 0.80 TAAR1 (0.43) CTBP2TAAR1
SCHEMBL30945894 0.77 DPP4 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704449-B1 Process for the preparation of diphosphanes CELANESE CHEM EUROPE GMBH (DE) 2000-05-24 EP disclosed
EP-0704449-A1 Diphosphanes and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-03 EP disclosed