Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | PPIB | P23284 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036105 | 0.95 | MLYCD (0.36) | MLYCDSMN1; SMN2MAPK1PPIBHTT | |
| SCHEMBL8030312 | 0.93 | NR1H4 (0.34) | MLYCDSMN1; SMN2NR1H4PDE5AHTT | |
| SCHEMBL8036249 | 0.89 | NR1H4 (0.41) | MLYCDSMN1; SMN2NR1H4MAPK1NPC1 | |
| SCHEMBL27473598 | 0.89 | MAPT (0.38) | MLYCDSMN1; SMN2MAPK1PPIBHTT | |
| SCHEMBL8030178 | 0.89 | MLYCD (0.39) | MLYCDSMN1; SMN2NR1H4PDE5AMAPK1 | |
| SCHEMBL8029986 | 0.89 | KMT2A (0.40) | SMN1; SMN2NR1H4MAPK1PPIBHTT | |
| SCHEMBL27487707 | 0.88 | KDM4E (0.35) | MLYCDSMN1; SMN2MAPK1PPIBHTT | |
| SCHEMBL27487343 | 0.88 | ITGB1 (0.34) | MLYCDSMN1; SMN2MAPK1PPIBHTT | |
| SCHEMBL8020823 | 0.88 | SMN1; SMN2 (0.40) | MLYCDSMN1; SMN2PDE5AMAPK1PPIB | |
| SCHEMBL8033859 | 0.88 | SMN1; SMN2 (0.44) | MLYCDSMN1; SMN2PDE5AMAPK1PPIB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |