Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | BLM | P54132 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | TDP2 | O95551 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439353 | 1.00 | MEN1 (0.41) | MEN1KMT2AMAPTLMNABLM | |
| SCHEMBL5940376 | 1.00 | MEN1 (0.41) | MEN1KMT2AMAPTLMNABLM | |
| SCHEMBL5940374 | 1.00 | MEN1 (0.41) | MEN1KMT2AMAPTLMNABLM | |
| SCHEMBL8260617 | 0.85 | IDO1 (0.35) | MEN1KMT2AMAPTLMNABLM | |
| SCHEMBL16298303 | 0.83 | MEN1 (0.39) | MEN1KMT2AMAPTLMNABLM | |
| SCHEMBL5940203 | 0.80 | IDO1 (0.37) | MEN1KMT2AMAPTLMNABLM | |
| SCHEMBL25704049 | 0.72 | EPHX2 (0.38) | MEN1KMT2ASMN1; SMN2RAB9APOLB | |
| SCHEMBL25704048 | 0.70 | IDO1 (0.37) | MEN1KMT2AMAPTLMNABLM | |
| SCHEMBL15256933 | 0.69 | ALDH1A1 (0.50) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL103949 | 0.69 | IDO1 (0.53) | MEN1KMT2AMAPTLMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009084834-A2 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF CARDIAC DISEASE | MAZENCE INC. (KR) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009082124-A2 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF GLAUCOMA | MAZENCE INC. (KR) | 2009-07-02 | — | — | WO | disclosed |