Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 2/20 | 0.39 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020547 | 0.99 | BDKRB2 (0.41) | BDKRB2NPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL8030202 | 0.94 | BDKRB2 (0.42) | BDKRB2NPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL8020853 | 0.94 | CASR (0.45) | BDKRB2RAB9ASMN1; SMN2CASRMEN1 | |
| SCHEMBL8030290 | 0.93 | BDKRB2 (0.42) | BDKRB2NPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL8030205 | 0.93 | CASR (0.42) | BDKRB2NPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL8030643 | 0.93 | CASR (0.46) | BDKRB2RAB9ASMN1; SMN2CASRMEN1 | |
| SCHEMBL8034123 | 0.93 | BDKRB2 (0.42) | BDKRB2NPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL8029973 | 0.92 | BDKRB2 (0.40) | BDKRB2NPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL8030420 | 0.91 | BDKRB2 (0.39) | BDKRB2NPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL8020871 | 0.90 | CNR1 (0.35) | BDKRB2CASRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |