Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL8956648 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNCA5ACA5B | |
| Sulfuric Acid SCHEMBL27904035 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNCA5ACA5B | |
| Sulfuric Acid SCHEMBL10783057 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNCA5ACA5B | |
| Sulfuric Acid SCHEMBL27396189 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNCA5ACA5B | |
| Sulfuric Acid SCHEMBL11315305 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNCA5ACA5B | |
| Sulfuric Acid SCHEMBL11328917 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNCA5ACA5B | |
| Sulfuric Acid SCHEMBL11544369 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNCA5ACA5B | |
| Sulfuric Acid SCHEMBL10378486 | 0.92 | FFAR3 (0.64) | FFAR3LCKFYNCA5ACA5B | |
| Sulfuric Acid SCHEMBL164130 | 0.92 | FFAR3 (0.64) | FFAR3LCKFYNCA5ACA5B | |
| Sulfuric Acid SCHEMBL7640374 | 0.92 | FFAR3 (0.64) | FFAR3LCKFYNCA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6042811-A | CONTAINING A PARTICULATE DRUG, A DIOL/DIACID CONDENSATE AS A DISPERSING AID AND A PROPELLANT | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| US-5725841-A | METERED DOSE INHALER | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| US-5569450-A | DRUG DELIVERY TO LUNGS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-10-29 | — | — | US | disclosed |
| EP-0689423-A1 | AEROSOL FORMULATION CONTAINING A DIOL-DIACID DERIVED DISPERSING AID | MINNESOTA MINING & MFG (US) | 1996-01-03 | — | — | EP | disclosed |
| EP-0689424-A1 | AEROSOL FORMULATION CONTAINING AN ESTER-, AMIDE-, OR MERCAPTOESTER-DERIVED DISPERSING AID | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-01-03 | — | — | EP | disclosed |
| WO-1994021229-A1 | AEROSOL FORMULATION CONTAINING AN ESTER-, AMIDE-, OR MERCAPTOESTER-DERIVED DISPERSING AID | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-09-29 | — | — | WO | disclosed |
| WO-1994021228-A1 | AEROSOL FORMULATION CONTAINING A DIOL-DIACID DERIVED DISPERSING AID | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-09-29 | — | — | WO | disclosed |