Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 11/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397440 | 0.87 | GNRHR (0.51) | GNRHRTLR8TLR7 | |
| SCHEMBL8344835 | 0.87 | GNRHR (0.63) | GNRHR | |
| SCHEMBL8184205 | 0.80 | GNRHR (0.67) | GNRHR | |
| SCHEMBL8176808 | 0.78 | GNRHR (0.59) | GNRHR | |
| SCHEMBL7829040 | 0.76 | GNRHR (0.51) | GNRHR | |
| SCHEMBL8695292 | 0.71 | GNRHR (0.81) | GNRHR | |
| SCHEMBL6985175 | 0.69 | GNRHR (0.53) | GNRHR | |
| SCHEMBL7899428 | 0.69 | GNRHR (0.51) | GNRHR | |
| SCHEMBL6981787 | 0.68 | GNRHR (0.51) | GNRHR | |
| SCHEMBL6983188 | 0.68 | GNRHR (0.52) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156772-A | INDOLE HORMONE INHIBITORS | MERCK & CO., INC. (US) | 2000-12-05 | — | — | US | disclosed |
| WO-2000069433-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 2000-11-23 | — | — | WO | disclosed |