Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CCR3 | P51677 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020713 | 0.99 | CASR (0.44) | CASREPHX2ALDH1A1CCR3MEN1 | |
| SCHEMBL8030420 | 0.94 | BDKRB2 (0.39) | CASREPHX2ALDH1A1CCR3MEN1 | |
| SCHEMBL8031876 | 0.94 | EPHX2 (0.40) | CASREPHX2ALDH1A1CCR3MEN1 | |
| SCHEMBL8020615 | 0.93 | EPHX2 (0.41) | CASREPHX2ALDH1A1CCR3MEN1 | |
| SCHEMBL8029973 | 0.93 | BDKRB2 (0.40) | CASREPHX2ALDH1A1CCR3MEN1 | |
| SCHEMBL8030264 | 0.93 | CASR (0.49) | CASREPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL8030643 | 0.92 | CASR (0.46) | CASREPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL8029962 | 0.92 | CASR (0.48) | CASREPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL8020853 | 0.92 | CASR (0.45) | CASREPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL8030371 | 0.91 | CASR (0.48) | CASREPHX2ALDH1A1CCR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |