Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033768 | 0.94 | MAPK1 (0.45) | MAPK1TP53CASP1CASP7HSD17B10 | |
| SCHEMBL8030236 | 0.93 | MAPK1 (0.48) | MAPK1TP53CASP1CASP7HSD17B10 | |
| SCHEMBL8030329 | 0.92 | MAPK1 (0.45) | MAPK1TP53CASP1CASP7HSD17B10 | |
| SCHEMBL8033743 | 0.92 | MAPK1 (0.46) | MAPK1TP53HTTKMT2AMEN1 | |
| SCHEMBL8034026 | 0.91 | MAPK1 (0.47) | MAPK1TP53CASP1CASP7HSD17B10 | |
| SCHEMBL8020593 | 0.90 | MAPK1 (0.45) | MAPK1TP53CASP1CASP7HSD17B10 | |
| SCHEMBL9133265 | 0.90 | NPC1 (0.45) | MAPK1TP53CASP1CASP7HSD17B10 | |
| SCHEMBL8036317 | 0.89 | MAPK1 (0.45) | MAPK1TP53CASP1CASP7HSD17B10 | |
| SCHEMBL8036340 | 0.89 | MAPK1 (0.45) | MAPK1TP53CASP1CASP7HSD17B10 | |
| SCHEMBL8030435 | 0.89 | MAPK1 (0.49) | MAPK1TP53HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |