Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030236 | 0.94 | MAPK1 (0.48) | NPC1SMN1; SMN2MAPK1TP53CASP1 | |
| SCHEMBL8034026 | 0.92 | MAPK1 (0.47) | NPC1SMN1; SMN2MAPK1TP53CASP1 | |
| SCHEMBL9131910 | 0.92 | RAB9A (0.49) | NPC1SMN1; SMN2ALDH1A1MAPTMAPK1 | |
| SCHEMBL8030329 | 0.91 | MAPK1 (0.45) | MAPK1TP53CASP1CASP7HSD17B10 | |
| SCHEMBL8033768 | 0.91 | MAPK1 (0.45) | NPC1MAPK1TP53CASP1CASP7 | |
| SCHEMBL8030435 | 0.91 | MAPK1 (0.49) | NPC1SMN1; SMN2MAPTMAPK1TP53 | |
| SCHEMBL8020593 | 0.91 | MAPK1 (0.45) | NPC1SMN1; SMN2MAPK1TP53CASP1 | |
| SCHEMBL8020599 | 0.91 | MAPK1 (0.46) | NPC1SMN1; SMN2MAPTMAPK1TP53 | |
| SCHEMBL8033743 | 0.91 | MAPK1 (0.46) | NPC1SMN1; SMN2MAPK1TP53RAB9A | |
| SCHEMBL8036051 | 0.91 | MAPK1 (0.56) | NPC1SMN1; SMN2ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475106-A | Agonist for cholecystokinin and gastrin receptors; nervous system, gastrointestinal disorders | RHONE-POULENC RORER S.A. (FR) | 1995-12-12 | — | — | US | disclosed |