⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670125 | 0.78 | LMNA (0.41) | — | |
| SCHEMBL1400080 | 0.71 | MEN1 (0.42) | — | |
| SCHEMBL3599353 | 0.71 | NPC1 (0.44) | — | |
| SCHEMBL29169316 | 0.69 | — | — | |
| SCHEMBL2956313 | 0.69 | — | — | |
| SCHEMBL329286 | 0.69 | — | — | |
| SCHEMBL29561298 | 0.69 | — | — | |
| SCHEMBL2325405 | 0.69 | — | — | |
| SCHEMBL17286589 | 0.67 | — | — | |
| Bromide SCHEMBL9622942 | 0.67 | NPC1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103153945-B | 1-oximino-3-phenyl-propanes | HOFFMAN-LA ROCHE LTD. (CH) | 2016-03-02 | — | — | CN | claimed |
| CN-110483484-A | Sulfamoyl pyrrole amides derivative and its purposes for being used to treat hepatitis B as drug | JANSSEN SCIENCES IRELAND UC | 2019-11-22 | — | — | CN | disclosed |
| CN-110325529-A | HERBICIDAL AZINES | 巴斯夫欧洲公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-105980378-B | Sulfamoyl pyrrole amide derivative and application thereof as medicine for treating hepatitis B | 爱尔兰詹森科学公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-107207515-B | Pyrazine compounds for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2019-05-28 | — | — | CN | disclosed |
| CN-106349156-B | It can be used as the pyridine -2- amides of CB2 agonist | 霍夫曼-拉罗奇有限公司 | 2018-12-11 | — | — | CN | disclosed |
| CN-105324379-B | Benzimidazole derivatives as bromodomain inhibitors | 吉利德科学公司 | 2018-12-04 | — | — | CN | disclosed |
| CN-104854092-B | Pyridine-2-amides useful as CB2 agonists | 霍夫曼-拉罗奇有限公司 | 2018-08-10 | — | — | CN | disclosed |
| CN-107207515-A | Pyrazine compounds for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-107148420-A | Benzyl substituted indazoles | 拜耳制药股份公司 | 2017-09-08 | — | — | CN | disclosed |
| CN-106349156-A | Pyridine-2-amides capable of being used as CB2 agonist | 霍夫曼-拉罗奇有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-103025331-B | Certain amino-pyrimidines, compositions thereof and methods of use thereof | CYTOKINETICS, INC. (US) | 2016-03-02 | — | — | CN | disclosed |
| CN-103153945-B | 1-oximino-3-phenyl-propanes | HOFFMAN-LA ROCHE LTD. (CH) | 2016-03-02 | — | — | CN | disclosed |
| CN-105324379-A | Benzimidazole derivatives as bromodomain inhibitors | GILEAD SCIENCES INC | 2016-02-10 | — | — | CN | disclosed |
| CN-104854092-A | PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS | HOFFMANN LA ROCHE | 2015-08-19 | — | — | CN | disclosed |
| CN-104822675-A | New indanyloxydihydrobenzofuranylacetic acids | BOEHRINGER INGELHEIM INT | 2015-08-05 | — | — | CN | disclosed |
| CN-104395458-A | Improving resistance to skeletal muscle fatigue | CYTOKINETICS INC | 2015-03-04 | — | — | CN | disclosed |
| CN-104379597-A | Method for improving diaphragm function | CYTOKINETICS INC | 2015-02-25 | — | — | CN | disclosed |
| CN-101965353-A | Covalently bound dicyclo nitro glyoxaline to the substituted benzene oxazolidinone | GLOBAL ALLIANCE FOR TB DRUG DEV | 2011-02-02 | — | — | CN | disclosed |
| US-6110987-A | CURED PRODUCTS HAVING AN EXCELLENT APPEARANCE WITHOUT COLORING CAUSED BY POLYMERIZATION INITIATOR | SHOWA DENKO K.K. (JP) | 2000-08-29 | — | — | US | disclosed |