Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL8029178 | 0.93 | LMNA (0.42) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL352004 | 0.89 | LMNA (0.50) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL26877 | 0.89 | — | — | |
| SCHEMBL9620428 | 0.89 | LMNA (0.50) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL2201832 | 0.89 | LMNA (0.50) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL20345 | 0.89 | LMNA (0.50) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL3778363 | 0.89 | LMNA (0.50) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL14839871 | 0.89 | LMNA (0.50) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL852700 | 0.89 | LMNA (0.50) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL5498280 | 0.89 | LMNA (0.50) | LMNATSHRALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000071680-A1 | A PROCESS FOR PRODUCING PROSTAGLANDIN SYNTHETASE AND PROSTAGLANDINS | SPHINX MILLENIUM PTY LTD (AU) | 2000-11-30 | — | — | WO | disclosed |