1,2-Dimethoxybenzene

1,2-Dimethoxybenzene

SCHEMBL8030772

COc1ccccc1OC.F[B-](F)(F)F.N#[NH+]

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.65
CA2 P00918 3/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA12 O43570 1/20 0.65
CA4 P22748 1/20 0.65
CA14 Q9ULX7 1/20 0.65
ALDH1A1 P00352 3/20 0.50
HTT P42858 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
MAPK1 P28482 2/20 0.50
TDP1 Q9NUW8 2/20 0.46
TP53 P04637 2/20 0.46
TSHR P16473 1/20 0.46
ADRA2B P18089 1/20 0.46
PTGS1 P23219 1/20 0.46
ENPP2 Q13822 1/20 0.43
ORAI1 Q96D31 1/20 0.41
ORAI2 Q96SN7 1/20 0.41
ORAI3 Q9BRQ5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Dimethoxybenzene SCHEMBL29178261 0.92 CA1 (0.77) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL15921081 0.90 CA1 (0.72) CA1CA2CA7CA9CA12
Nitrogen SCHEMBL9672420 0.85 L3MBTL1 (0.47) CA1CA2CA7CA9CA12
Nitrogen SCHEMBL28211174 0.84 SMN1; SMN2 (0.47) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL7895992 0.81 CA1 (0.87) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL28757168 0.81 CA1 (0.87) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL105872 0.81 CA1 (1.00) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL5308636 0.81 CA1 (1.00) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL29351917 0.81 CA1 (1.00) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL11638262 0.78 CA1 (0.81) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106045836-B A kind of method of copper catalysis synthesis aromatic hydrocarbons or heterocycle trifluoromethyl ketone 福州大学 2018-04-13 CN disclosed
US-6015621-A Ultraviolet dosimeter film Syntec Gesellschaft fur Chemie und Technologie der Informationsaufzeichnu ng mbH (DE) 2000-01-18 US disclosed