Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391872 | 0.87 | TSHR (0.50) | CCR6PAX8TSHRLPAR1TDP1 | |
| SCHEMBL393311 | 0.87 | TSHR (0.47) | CCR6PAX8TSHRLPAR1TDP1 | |
| SCHEMBL16295819 | 0.86 | TSHR (0.51) | CCR6PAX8TSHRLPAR1TDP1 | |
| SCHEMBL8029008 | 0.86 | CCR6 (0.56) | CCR6PAX8LPAR1GAAMAPT | |
| SCHEMBL393336 | 0.85 | TSHR (0.48) | CCR6PAX8TSHRLPAR1TDP1 | |
| SCHEMBL4668991 | 0.84 | TSHR (0.54) | TSHRLPAR1TDP1POLBGAA | |
| SCHEMBL8032608 | 0.84 | CCR6 (0.52) | CCR6PAX8KMT2A | |
| SCHEMBL15582141 | 0.84 | CCR6 (0.61) | CCR6PAX8TDP1L3MBTL1MEN1 | |
| SCHEMBL19018818 | 0.84 | CCR6 (0.61) | CCR6PAX8TDP1L3MBTL1MEN1 | |
| SCHEMBL9110508 | 0.84 | CCR6 (0.61) | CCR6PAX8TDP1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797579-B1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON SPA (IT) | 2000-03-15 | — | — | EP | disclosed |