Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030776 | 0.84 | CCR6 (0.54) | CCR6PAX8KMT2A | |
| SCHEMBL8029008 | 0.84 | CCR6 (0.56) | CCR6PAX8PTGDR2KMT2ALMNA | |
| SCHEMBL19018818 | 0.82 | CCR6 (0.61) | CCR6PAX8KMT2ACNR2 | |
| SCHEMBL9110508 | 0.82 | CCR6 (0.61) | CCR6PAX8KMT2ACNR2 | |
| SCHEMBL15582141 | 0.82 | CCR6 (0.61) | CCR6PAX8KMT2ACNR2 | |
| SCHEMBL6264786 | 0.82 | CCR6 (0.57) | CCR6PAX8LIMK2KMT2ALMNA | |
| SCHEMBL14823650 | 0.82 | CCR6 (0.56) | CCR6PAX8LIMK2KMT2ALMNA | |
| SCHEMBL16586897 | 0.81 | CCR6 (0.63) | CCR6PAX8KMT2ALMNACNR2 | |
| SCHEMBL10823051 | 0.80 | CCR6 (0.62) | CCR6PAX8KMT2ACNR2 | |
| SCHEMBL10822625 | 0.80 | CCR6 (0.62) | CCR6PAX8KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797579-B1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON SPA (IT) | 2000-03-15 | — | — | EP | disclosed |