Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449074 | 1.00 | NR5A1 (0.56) | NR5A1HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL5441253 | 1.00 | NR5A1 (0.56) | NR5A1HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL23648812 | 1.00 | NR5A1 (0.56) | NR5A1HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL9523100 | 1.00 | NR5A1 (0.56) | NR5A1HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL10900013 | 0.95 | HPGD (0.55) | NR5A1HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL10899112 | 0.95 | HPGD (0.55) | NR5A1HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL10898783 | 0.95 | HPGD (0.55) | NR5A1HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL1823685 | 0.95 | LTA4H (0.48) | NR5A1KDM4ELTA4HTSHR | |
| SCHEMBL10900140 | 0.93 | HPGD (0.52) | NR5A1HPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL9570661 | 0.91 | HRH3 (0.44) | NR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000071118-A1 | PHOSPHOLIPASE A2-SPECIFIC INHIBITING COMPOUNDS | UNIVERSITE PARIS 7 - DENIS DIDEROT (FR) | 2000-11-30 | — | — | WO | disclosed |