Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | CDC25A | P30304 | 2/20 | 0.35 |
| ▸ | CDC25B | P30305 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19117572 | 0.76 | CDC25A (0.37) | CDC25ACDC25BPTPN1IDO1GAA | |
| SCHEMBL6443437 | 0.75 | HTR6 (0.33) | HTR6 | |
| SCHEMBL6911205 | 0.74 | CDC25A (0.36) | CDC25ACDC25BPTPN1IDO1GAA | |
| SCHEMBL27924201 | 0.74 | GAA (0.38) | CDC25ACDC25BPTPN1IDO1GAA | |
| SCHEMBL7939907 | 0.74 | HTR6 (0.41) | HTR6POLBKDM4ELMNATP53 | |
| SCHEMBL13237438 | 0.73 | CDC25A (0.35) | CDC25ACDC25BPTPN1IDO1GAA | |
| SCHEMBL9755397 | 0.72 | CDC25A (0.38) | CDC25ACDC25BPTPN1IDO1GAA | |
| SCHEMBL6129625 | 0.69 | HTR6 (0.39) | HTR6GPR3HTR2ACHRM2HTR1A | |
| SCHEMBL28467281 | 0.69 | CDC25A (0.36) | CDC25ACDC25BPTPN1IDO1GAA | |
| Hydrochloric Acid SCHEMBL8043033 | 0.68 | CYP19A1 (0.33) | CDC25ACDC25BPTPN1IDO1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087292-A | Metallocene catalysts comprising indenyl ligands substituted with electronegative groups | TANGOR GMBH (DE) | 2000-07-11 | — | — | US | disclosed |
| US-5763542-A | Process for the preparation of an olefin polymer using specific metallocenes | TARGOR GMBH (DE) | 1998-06-09 | — | — | US | disclosed |
| US-5504232-A | Process for the preparation of an olefin polymer using specific metallocenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |
| EP-0582195-A1 | Process for the preparation of polymers using specific metallocenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-09 | — | — | EP | disclosed |