SCHEMBL803109

SCHEMBL803109

Cc1nn(C)nc1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18643119 0.77
SCHEMBL14844938 0.77
SCHEMBL11739484 0.77
SCHEMBL8915199 0.71 POLB (0.32)
SCHEMBL16688421 0.71
SCHEMBL8915968 0.71
SCHEMBL1412465 0.71
SCHEMBL13312892 0.71
SCHEMBL12204478 0.67 ADORA2A (0.41)
SCHEMBL16501144 0.66 ADORA2A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2763970-A1 ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS Syngenta Participations AG (CH) 2014-08-13 EP claimed
WO-2013050302-A1 ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2013-04-11 WO claimed
US-20230212091-A1 Compositions for Increasing Nitrogen Sources Life Span in Plant Growth Mediums and Methods of Making SOILGENIC TECHNOLOGIES, LLC 2023-07-06 US disclosed
WO-2023122600-A1 PIPERAZINE INDAZOLE GLUCOCORTICOID RECEPTOR ANTAGONISTS CORCEPT THERAPEUTICS INCORPORATED (US) 2023-06-29 WO disclosed
US-20230174492-A1 SUBSTITUTED CONDENSED AZINES AS ANTHELMINTIC COMPOUNDS ELANCO ANIMAL HEALTH GMBH (DE) 2023-06-08 US disclosed
US-20230041518-A1 QUINOLINE DERIVATIVES GILEAD SCIENCES, INC. 2023-02-09 US disclosed
US-11548854-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2023-01-10 US disclosed
US-11542278-B1 Heteroaromatic macrocyclic ether chemotherapeutic agents NUVALENT, INC. (US) 2023-01-03 US disclosed
US-20220340576-A1 SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF RELAY THERAPEUTICS, INC. 2022-10-27 US disclosed
EP-3544971-B1 INHIBITORS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF DANA FARBER CANCER INST INC (US) 2022-07-06 EP disclosed
EP-4019515-A1 INHIBITORS OF CYCLIN-DEPENDENT KINASES Dana-Farber Cancer Institute, Inc. (US) 2022-06-29 EP disclosed
US-20090004597-A1 Photosensitive Composition, Display Member, and Process for Producing The Same TORAY INDUSTRIES, INC. (JP) 2009-01-01 US disclosed
US-7438898-B1 Hair conditioning composition comprising carboxylic acid/carboxylate copolymer, and visible particle THE PROCTER & GAMBLE COMPANY (US) 2008-10-21 US disclosed
US-7438898-B1 Hair conditioning composition comprising carboxylic acid/carboxylate copolymer, and visible particle THE PROCTER & GAMBLE COMPANY (US) 2008-10-21 US disclosed
US-7439253-B2 Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors NOVEXEL (FR) 2008-10-21 US disclosed
EP-1980910-A1 PHOTOSENSITIVE COMPOSITION, DISPLAY MEMBER, AND PROCESS FOR PRODUCING THE SAME TORAY INDUSTRIES, INC. (JP) 2008-10-15 EP disclosed
US-20080027226-A1 Electroluminescent Device CIBA SPECIALTY CHEMICALS CORP. 2008-01-31 US disclosed
US-20080015355-A1 Electroluminescent Metal Complexes With Triazoles And Benzotriazoles UDC IRELAND LIMITED (IE) 2008-01-17 US disclosed
US-20070043204-A1 Novel polymers comprising benzotriazole for use in optical devices CIBA SPECIALITY CHEMICALS CORP. 2007-02-22 US disclosed
WO-2004072243-A2 MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS ENANTA PHARMACEUTICALS, INC. (US) 2004-08-26 WO disclosed