SCHEMBL8915199

SCHEMBL8915199

Cc1nn(C)nc1C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17917760 0.84 POLB (0.35) POLB
SCHEMBL14663933 0.77 ADORA2A (0.30)
SCHEMBL12281715 0.75 POLB (0.32) POLB
SCHEMBL803109 0.71
SCHEMBL13545656 0.70 GAA (0.31)
SCHEMBL18459512 0.69
SCHEMBL1412458 0.69 GAA (0.33)
SCHEMBL1412616 0.69
SCHEMBL936108 0.67 GLA (0.37) POLB
SCHEMBL18516444 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2652139-B1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF AGRO BV (NL) 2021-10-20 EP disclosed
US-20140256728-A1 COMPOUNDS WITH NEMATICIDAL ACTIVITY BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-09-11 US disclosed
US-20140256728-A1 COMPOUNDS WITH NEMATICIDAL ACTIVITY BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-09-11 US disclosed
EP-2589294-A1 Compounds with nematicidal activity Bayer CropScience AG (DE) 2013-05-08 EP disclosed
US-8324263-B2 Microbiocidally active carboxamides SYNGENTA CROP PROTECTION, LLC (US) 2012-12-04 US disclosed
US-8202894-B2 Microbiocides SYNGENTA CROP PROTECTION LLC (US) 2012-06-19 US disclosed
US-8188088-B2 Ethenyl carboxamide derivatives useful as microbiocides SYNGENTA PARTICIPATIONS AG (CH) 2012-05-29 US disclosed
US-8188088-B2 Ethenyl carboxamide derivatives useful as microbiocides SYNGENTA PARTICIPATIONS AG (CH) 2012-05-29 US disclosed
US-20110207771-A1 N-(L-ALKYL-2-PHENYLETHYL)-CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES SYNGENTA CROP PROTECTION, INC. (US) 2011-08-25 US disclosed
US-20110207771-A1 N-(L-ALKYL-2-PHENYLETHYL)-CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES SYNGENTA CROP PROTECTION, INC. (US) 2011-08-25 US disclosed
US-20100292239-A1 NOVEL MICROBIOCIDES SYNGENTA CROP PROTECTION, INC. (US) 2010-11-18 US disclosed
US-20100227898-A1 NOVEL MICROBIOCIDES SYNGENTA CROP PROTECTION, INC. (US) 2010-09-09 US disclosed
US-20100190794-A1 Herbicidally Active Composition BASF SE (DE) 2010-07-29 US disclosed
US-20090318495-A1 ETHENYL CARBOXAMIDE DERIVATIVES USEFUL AS MICROBIOCIDES SYNGENTA CROP PROTECTION, INC. (US) 2009-12-24 US disclosed
US-20090318495-A1 ETHENYL CARBOXAMIDE DERIVATIVES USEFUL AS MICROBIOCIDES SYNGENTA CROP PROTECTION, INC. (US) 2009-12-24 US disclosed
WO-2009012998-A1 NOVEL MICROBIOCIDES SYNGENTA PARTICIPATIONS AG (CH) 2009-01-29 WO disclosed
WO-2009003672-A2 NOVEL MICROBIOCIDES SYNGENTA PARTICIPATIONS AG (CH) 2009-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140256728-A1 COMPOUNDS WITH NEMATICIDAL ACTIVITY ACHE, TUBA3C, NAAA POLB 2389/4885
US-20100227898-A1 NOVEL MICROBIOCIDES FPR1, CD14, MSR1 POLB 2588/4885
US-20110207771-A1 N-(L-ALKYL-2-PHENYLETHYL)-CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES CYP1A1, CYP51A1, CYP2E1 POLB 3807/4885
US-20100190794-A1 Herbicidally Active Composition ECI1, ACLY, SQOR POLB 545/4885
US-20090318495-A1 ETHENYL CARBOXAMIDE DERIVATIVES USEFUL AS MICROBIOCIDES CD14, MSR1, ELANE POLB 836/4885
US-20100292239-A1 NOVEL MICROBIOCIDES CD14, FPR1, MPO POLB 2168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.