Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5686769 | 1.00 | EPHX1 (0.46) | EPHX1ALDH1A1TP53DPP4SMN1; SMN2 | |
| SCHEMBL360610 | 1.00 | EPHX1 (0.46) | EPHX1ALDH1A1TP53DPP4SMN1; SMN2 | |
| SCHEMBL67018 | 1.00 | EPHX1 (0.46) | EPHX1ALDH1A1TP53DPP4SMN1; SMN2 | |
| SCHEMBL503695 | 1.00 | EPHX1 (0.46) | EPHX1ALDH1A1TP53DPP4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5515976 | 0.97 | EPHX1 (0.44) | EPHX1ALDH1A1TP53DPP4SMN1; SMN2 | |
| SCHEMBL16837771 | 0.97 | EPHX1 (0.42) | EPHX1ALDH1A1TP53DPP4SMN1; SMN2 | |
| SCHEMBL4412203 | 0.97 | EPHX1 (0.42) | EPHX1ALDH1A1TP53DPP4SMN1; SMN2 | |
| SCHEMBL8031374 | 0.97 | EPHX1 (0.42) | EPHX1ALDH1A1TP53DPP4SMN1; SMN2 | |
| Benzene SCHEMBL18322786 | 0.92 | EPHX1 (0.39) | EPHX1ALDH1A1TP53KDM4EMAPT | |
| SCHEMBL16837724 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121241-A | TREATING CARDIOVASCULAR DISORDERS | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2000-09-19 | — | — | US | disclosed |
| EP-0863871-B1 | ANTICOAGULANT PEPTIDE ALDEHYDE DERIVATIVES | GYOGYSZERKUTATO INTEZET (HU) | 2000-03-08 | — | — | EP | disclosed |
| EP-0863871-A1 | ANTICOAGULANT PEPTIDE ALDEHYDE DERIVATIVES | GYOGYSZERKUTATO INTEZET KFT. (HU) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997046523-A1 | ANTICOAGULANT PEPTIDE ALDEHYDE DERIVATIVES | Gyógyszerkutató Intézet Kft. (HU) | 1997-12-11 | — | — | WO | disclosed |