Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5686769 | 1.00 | EPHX1 (0.46) | EPHX1ALDH1A1TP53DPP4SMN1; SMN2 | |
| SCHEMBL360610 | 1.00 | EPHX1 (0.46) | EPHX1ALDH1A1TP53DPP4SMN1; SMN2 | |
| SCHEMBL8031276 | 1.00 | EPHX1 (0.46) | EPHX1ALDH1A1TP53DPP4SMN1; SMN2 | |
| SCHEMBL67018 | 1.00 | EPHX1 (0.46) | EPHX1ALDH1A1TP53DPP4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5515976 | 0.97 | EPHX1 (0.44) | EPHX1ALDH1A1TP53DPP4SMN1; SMN2 | |
| SCHEMBL16837771 | 0.97 | EPHX1 (0.42) | EPHX1ALDH1A1TP53DPP4SMN1; SMN2 | |
| SCHEMBL4412203 | 0.97 | EPHX1 (0.42) | EPHX1ALDH1A1TP53DPP4SMN1; SMN2 | |
| SCHEMBL8031374 | 0.97 | EPHX1 (0.42) | EPHX1ALDH1A1TP53DPP4SMN1; SMN2 | |
| Benzene SCHEMBL18322786 | 0.92 | EPHX1 (0.39) | EPHX1ALDH1A1TP53KDM4EMAPT | |
| SCHEMBL16837724 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 468 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| EP-3141284-B1 | METHOD OF STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE | OREAL (FR) | 2019-08-28 | — | — | EP | claimed |
| CN-106916177-B | A kind of deuterated dipeptide boronic acid or its ester type compound and its synthetic method and purposes | 南京陵瑞医药科技有限公司 | 2019-04-23 | — | — | CN | claimed |
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-09-11 | — | — | US | claimed |
| EP-2346882-B1 | DERIVATIVES OF 1-AMINO-2-CYCLOBUTYLETHYLBORONIC ACID | MILLENNIUM PHARM INC (US) | 2017-09-20 | — | — | EP | claimed |
| EP-2029237-B1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE | ORÉAL L (FR) | 2016-10-12 | — | — | EP | claimed |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | Indiana University Research and Technology Corpora tion (US) | 2016-06-23 | — | — | US | claimed |
| US-20160074296-A1 | METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND AN a-HYDROXY ACID DERIVATIVE | L'OREAL (FR) | 2016-03-17 | — | — | US | claimed |
| US-9217012-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-12-22 | — | — | US | claimed |
| US-5589277-A | INK JET PRINTING, AQUEOUS INKS, FAST DRYING | XEROX CORPORATION (US) | 1996-12-31 | — | — | US | claimed |
| US-5561157-A | INCLUDES ORGANIC ALPHA AND BETA HYDROXY OR KETO CARBOXYLIC ACIDS, ESTERS, LACTONES AND/OR SALTS; USED FOR SKIN DISORDERS | TRISTRATA INC (US) | 1996-10-01 | — | — | US | claimed |
| US-5561158-A | Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging | TRISTRATA, INCORPORATED | 1996-10-01 | — | — | US | claimed |
| US-5554597-A | Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging | TRISTRATA INC (US) | 1996-09-10 | — | — | US | claimed |
| US-5554652-A | TOPICALLY APPLYING MIXTURE TO REDUCE OR PREVENT SKIN DISORDERS | TRISTRATA INC (US) | 1996-09-10 | — | — | US | claimed |
| US-5554654-A | COMPRISING SALICYLIC ACID, RETINOIC ACID, ERYTHROMYCIN, METRONIDAZOLE, TETRACYCLINE, CLINDAMYCIN, MINOCYCLINE, MECLOCYCLINE OR BENZILIC ACID BY COMBINING WITH 2-HYDROXY ACID, 2-KETOACID, DERIVATIVE THEREOF OR RELATED COMPOUND | TRISTRATA INC (US) | 1996-09-10 | — | — | US | claimed |
| EP-0667246-A1 | Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds | XEROX CORPORATION (US) | 1995-08-16 | — | — | EP | claimed |
| EP-0273202-B1 | Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. | SCOTT EUGENE J VAN (US) | 1995-06-21 | — | — | EP | claimed |
| EP-0599819-A2 | Additives enhancing topical actions of therapeutic agents | Van Scott, Eugene J., Dr. (US) | 1994-06-01 | — | — | EP | claimed |
| EP-0273202-A2 | Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. | Van Scott, Eugene J., Dr. (US) | 1988-07-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | PTPRCAP, PTPRF, PTPRS | EPHX1 1402/4885ALDH1A1 3087/4885TP53 234/4885 |
| US-20160074296-A1 | METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND AN a-HYDROXY ACID DERIVATIVE | KRT18, HOGA1, CYP27B1 | EPHX1 1241/4885ALDH1A1 175/4885TP53 4263/4885 |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | EPHX1 1402/4885ALDH1A1 3087/4885TP53 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.