Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
| ▸ | AGT | P01019 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979804 | 0.93 | AGT (0.45) | AGTR1AGTR2AGT | |
| SCHEMBL8028180 | 0.93 | AGTR1 (0.45) | AGTR1AGTR2AGT | |
| SCHEMBL8028153 | 0.90 | AGTR1 (0.47) | AGTR1AGTR2AGT | |
| SCHEMBL8034108 | 0.88 | AGTR1 (0.45) | AGTR1AGTR2AGT | |
| SCHEMBL9274865 | 0.87 | AGT (0.43) | AGTR1AGTR2AGT | |
| SCHEMBL8028318 | 0.87 | AGTR1 (0.44) | AGTR1AGTR2AGT | |
| SCHEMBL8018483 | 0.85 | — | — | |
| SCHEMBL8979874 | 0.83 | AGT (0.51) | AGTR1AGTR2AGT | |
| SCHEMBL8034105 | 0.83 | AGTR1 (0.47) | AGTR1AGTR2AGT | |
| SCHEMBL8028326 | 0.82 | AGTR1 (0.46) | AGTR1AGTR2AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096754-A | N-3 substituted pyrimidin-4-ones with AII antagonistic activity | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 2000-08-01 | — | — | US | disclosed |