⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130087 | 0.91 | — | — | |
| SCHEMBL8028142 | 0.90 | — | — | |
| SCHEMBL8018483 | 0.89 | — | — | |
| SCHEMBL8029901 | 0.89 | AGTR1 (0.39) | — | |
| Milfasartan SCHEMBL489256 | 0.89 | — | — | |
| SCHEMBL7995713 | 0.87 | — | — | |
| SCHEMBL9848932 | 0.87 | PPARG (0.49) | — | |
| SCHEMBL9848939 | 0.86 | AGTR1 (0.46) | — | |
| SCHEMBL614096 | 0.86 | — | — | |
| SCHEMBL9848915 | 0.85 | AGTR1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096754-A | N-3 substituted pyrimidin-4-ones with AII antagonistic activity | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 2000-08-01 | — | — | US | disclosed |