SCHEMBL8031341

SCHEMBL8031341

CCCCCCCC/C=C\CCCCCCCCC1CNC(CCCO)=N1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.36
PSMD14 O00487 1/20 0.36
RAD52 P43351 1/20 0.36
EPHX2 P34913 3/20 0.35
TRPV1 Q8NER1 1/20 0.33
GMNN O75496 1/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
ALOX15 P16050 1/20 0.33
APEX1 P27695 1/20 0.33
CYP2C19 P33261 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HSD17B10 Q99714 1/20 0.33
DUSP3 P51452 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217509 0.95 EPHX2 (0.35) MMP2EPHX2TRPV1GMNNUSP2
SCHEMBL8038258 0.93 PSMD14 (0.40) MMP2PSMD14RAD52LMNAHSD17B10
SCHEMBL8035780 0.93 PSMD14 (0.40) MMP2PSMD14RAD52LMNAHSD17B10
SCHEMBL8032041 0.93 PSMD14 (0.40) MMP2PSMD14RAD52LMNAHSD17B10
SCHEMBL8022094 0.93 PSMD14 (0.40) MMP2PSMD14RAD52LMNAHSD17B10
SCHEMBL8031904 0.93 PSMD14 (0.40) MMP2PSMD14RAD52LMNAHSD17B10
SCHEMBL8038164 0.93 PSMD14 (0.40) MMP2PSMD14RAD52LMNAHSD17B10
SCHEMBL7158875 0.90 EPHX2 (0.38) EPHX2TRPV1GMNNUSP2LMNA
SCHEMBL9098243 0.90 EPHX2 (0.38) EPHX2TRPV1GMNNUSP2LMNA
SCHEMBL8022160 0.89 EPHX2 (0.35) MMP2EPHX2TRPV1GMNNUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6042750-A TETRAALKYLAMMONIUM HALIDE, ALKYLENEDIAMINE, ALIPHATIC HYDROCARBON HYDROXY IMIDAZOLINE, POLYOXYETHYLENE GLYCOL ESTERS AND AMINES, TRIALKANOLAMINE, AND AMINE OXYALKYLATE; PIPES Docter, Joan (US) 2000-03-28 US disclosed