SCHEMBL8031360

SCHEMBL8031360

CCCC1CCC(CCC2CCC(CC=O)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.35
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
CYP1A2 P05177 1/20 0.33
TLR4 O00206 2/20 0.30
MEN1 O00255 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8755971 1.00 CYP2C9 (0.35) CYP2C9ALDH1A1LMNAMAPTCYP1A2
SCHEMBL8755977 1.00 CYP2C9 (0.35) CYP2C9ALDH1A1LMNAMAPTCYP1A2
SCHEMBL2207128 0.98 CYP2C9 (0.36) CYP2C9ALDH1A1LMNAMAPTCYP1A2
SCHEMBL8753103 0.98 CYP2C9 (0.36) CYP2C9ALDH1A1LMNAMAPTCYP1A2
SCHEMBL9625923 0.91 TLR4 (0.38) CYP2C9ALDH1A1LMNAMAPTCYP1A2
SCHEMBL1509950 0.91 TLR4 (0.38) CYP2C9ALDH1A1LMNAMAPTCYP1A2
SCHEMBL9625925 0.91 TLR4 (0.38) CYP2C9ALDH1A1LMNAMAPTCYP1A2
SCHEMBL8755857 0.87 CYP1A2 (0.50) CYP2C9LMNAMAPTCYP1A2TLR4
SCHEMBL8755860 0.87 CYP1A2 (0.50) CYP2C9LMNAMAPTCYP1A2TLR4
SCHEMBL8755867 0.87 CYP1A2 (0.50) CYP2C9LMNAMAPTCYP1A2TLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6013198-A LIQUID CRYSTALLINE COMPOUNDS MODIFIED TO HAVE A TRIFLUOROMETHYLPHENYL GROUP OR TRIFLUOROMETHOXYPHENYL GROUP AS EXAMPLE OF KNOWN TERMINAL SUBSTITUENT; CHEMICAL STABILITY, HIGH VOLTAGE HOLDING RATIO, GOOD UV STABILITY CHISSO CORPORATION (JP) 2000-01-11 US disclosed
EP-0597701-B1 Conjugated enyne derivative and liquid crystal composition CHISSO CORP (JP) 1997-04-16 EP disclosed
EP-0761799-A1 Liquid crystalline compound substituted with fluorine containing group, liquid crystal composition, and liquid crystal display device Chisso Corporation (JP) 1997-03-12 EP disclosed
US-5370819-A Low viscosity CHISSO CORPORATION (JP) 1994-12-06 US disclosed
EP-0597701-A1 Conjugated enyne derivative and liquid crystal composition CHISSO CORPORATION (JP) 1994-05-18 EP disclosed