SCHEMBL9625925

SCHEMBL9625925

CCC[C@H]1CC[C@H]([C@H]2CC[C@H](CC=O)CC2)CC1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 2/20 0.38
CYP2C9 P11712 1/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9625923 1.00 TLR4 (0.38) TLR4CYP2C9ALDH1A1LMNAMAPT
SCHEMBL1509950 1.00 TLR4 (0.38) TLR4CYP2C9ALDH1A1LMNAMAPT
SCHEMBL8753103 0.94 CYP2C9 (0.36) TLR4CYP2C9ALDH1A1LMNAMAPT
SCHEMBL2207128 0.94 CYP2C9 (0.36) TLR4CYP2C9ALDH1A1LMNAMAPT
SCHEMBL8755971 0.91 CYP2C9 (0.35) TLR4CYP2C9ALDH1A1LMNAMAPT
SCHEMBL8755977 0.91 CYP2C9 (0.35) TLR4CYP2C9ALDH1A1LMNAMAPT
SCHEMBL8031360 0.91 CYP2C9 (0.35) TLR4CYP2C9ALDH1A1LMNAMAPT
SCHEMBL1249367 0.88 CYP1A2 (0.47) TLR4CYP2C9ALDH1A1LMNAMAPT
SCHEMBL9060505 0.86 CYP1A2 (0.41) CYP2C9LMNAMAPTCYP1A2
SCHEMBL8754355 0.86 CYP1A2 (0.41) CYP2C9LMNAMAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0325796-B1 A LIQUID CRYSTAL COMPOUND AND A MIXTURE CONTAINING THE SAME Chisso Corporation (JP) 1992-03-11 EP disclosed
US-4877548-A STABLE TO HEAT, LIGHT, ELECTRICITY AND MOISTURE CHISSO CORPORATION (JP) 1989-10-31 US disclosed
EP-0325796-A1 A liquid crystal compound and a mixture containing the same Chisso Corporation (JP) 1989-08-02 EP disclosed