SCHEMBL8031977

SCHEMBL8031977

Nc1c(N)c(-c2ccccc2)c(-c2ccccc2)c2c1Cc1ccccc1-2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.47
ADORA1 P30542 1/20 0.47
ACHE P22303 6/20 0.43
BCHE P06276 1/20 0.43
KDR P35968 3/20 0.41
MAP3K9 P80192 2/20 0.41
MAP3K11 Q16584 2/20 0.41
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
PNMT P11086 1/20 0.38
SQOR Q9Y6N5 1/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
NPC1 O15118 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29177879 0.95 ADORA2A (0.49) ADORA2AADORA1ACHEBCHEKDR
SCHEMBL28305768 0.90 ADORA2A (0.47) ADORA2AADORA1ACHEBCHEKDR
SCHEMBL8031980 0.88 ADORA2A (0.49) ADORA2AADORA1ACHEBCHEKDR
SCHEMBL27927828 0.84 ADORA2A (0.49) ADORA2AADORA1ACHEBCHEKDR
SCHEMBL29730500 0.83 MAP3K9 (0.46) ADORA2AADORA1ACHEBCHEKDR
SCHEMBL31123421 0.83 MAP3K9 (0.46) ADORA2AADORA1ACHEBCHEKDR
SCHEMBL28145785 0.83 MAP3K9 (0.46) ADORA2AADORA1ACHEBCHEKDR
SCHEMBL1877817 0.83 ACHE (0.45) ADORA2AADORA1ACHEBCHEKDR
SCHEMBL29177882 0.82 ADORA2A (0.44) ADORA2AADORA1ACHEBCHEKDR
SCHEMBL29177845 0.79 ADORA2A (0.41) ADORA2AADORA1ACHEBCHEKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024140402-A1 PREPARATION METHOD FOR MODIFIED MALEIMIDE PREPOLYMER, RESIN COMPOSITION, AND APPLICATION OF RESIN COMPOSITION 苏州生益科技有限公司 2024-07-04 WO claimed
WO-2024140402-A1 PREPARATION METHOD FOR MODIFIED MALEIMIDE PREPOLYMER, RESIN COMPOSITION, AND APPLICATION OF RESIN COMPOSITION 苏州生益科技有限公司 2024-07-04 WO disclosed
CN-110673233-B Optical film, flexible display device, and method for manufacturing optical film 住友化学株式会社 2022-11-15 CN disclosed
US-6027794-A Prepregs, processes for their production, and composite laminates TORAY INDUSTRIES, INC. (JP) 2000-02-22 US disclosed
EP-0632087-B1 PREPREG, METHOD OF MANUFACTURING THE SAME, AND LAMINATED COMPOSITE TORAY INDUSTRIES (JP) 1999-08-18 EP disclosed
EP-0632087-A1 PREPREG, METHOD OF MANUFACTURING THE SAME, AND LAMINATED COMPOSITE TORAY INDUSTRIES, INC. (JP) 1995-01-04 EP disclosed