SCHEMBL8032033

SCHEMBL8032033

CC(C)Cc1c(S(=O)(=O)O)c(S(=O)(=O)O)c2ccccc2c1CC(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
CNR1 P21554 2/20 0.33
CNR2 P34972 2/20 0.33
SLC2A1 P11166 1/20 0.33
CFTR P13569 1/20 0.33
CYP2D6 P10635 1/20 0.33
ELANE P08246 1/20 0.33
FABP3 P05413 1/20 0.33
FABP4 P15090 1/20 0.33
FABP5 Q01469 1/20 0.33
FBP1 P09467 1/20 0.32
TSHR P16473 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2521780 0.81 CYP2D6 (0.35) SLC2A1CYP2D6TSHRSMN1; SMN2TDP1
SCHEMBL10630609 0.79 TTR (0.32) PTGS1PTGS2ELANEFBP1TSHR
SCHEMBL4097604 0.79 TTR (0.32) PTGS1PTGS2ELANEFBP1TSHR
SCHEMBL2520071 0.75 KDM4E (0.41) CYP1A2SLC2A1CFTRCYP2D6TSHR
SCHEMBL7779121 0.75 KDM4E (0.41) CYP1A2SLC2A1CFTRCYP2D6TSHR
SCHEMBL29720 0.74 CYP2D6 (0.43) CYP1A2CNR1CNR2SLC2A1CYP2D6
SCHEMBL6555708 0.74 CYP2D6 (0.40) CNR1CNR2SLC2A1CYP2D6FABP3
SCHEMBL29364308 0.74 CYP2D6 (0.43) CYP1A2CNR1CNR2SLC2A1CYP2D6
SCHEMBL2521849 0.74 CYP2D6 (0.35) SLC2A1CYP2D6TSHRSMN1; SMN2TDP1
SCHEMBL11523759 0.73 KDM4E (0.40) CYP1A2SLC2A1CFTRCYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6102997-A COLORED INK APPLIED TO RECORDING MATERIAL WITH INK JET NOZZLE AGFA GEVAERT N.V. (BE) 2000-08-15 US disclosed
US-4983478-A Burn-in gumming composition for offset printing plates HOECHST AKTIENGESELLSCHAFT (DE) 1991-01-08 US disclosed
US-4885230-A Burn-in gumming composition for offset printing plates HOECHST AKTIENGESELLSCHAFT (DE) 1989-12-05 US disclosed
US-4370424-A PHENOL, SULFONIC ACID, ALDEHYDE, SURFACTANT SCHAUM-CHEMIE W. BAUER GMBH & CO KG (DE) 1983-01-25 US disclosed