Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020962 | 0.92 | CASR (0.37) | CASRKMT2AMEN1ALDH1A1BDKRB2 | |
| SCHEMBL8036625 | 0.92 | CASR (0.44) | CASRKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL8031781 | 0.91 | KMT2A (0.35) | CASRKMT2AMEN1ALDH1A1BDKRB2 | |
| SCHEMBL8033754 | 0.90 | KMT2A (0.35) | CASRKMT2AMEN1ALDH1A1BDKRB2 | |
| SCHEMBL8030124 | 0.89 | CASR (0.43) | CASRKMT2AMEN1ALDH1A1BDKRB2 | |
| SCHEMBL8030648 | 0.88 | KMT2A (0.36) | CASRKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL8031923 | 0.88 | MAPK1 (0.39) | CASRKMT2AMEN1HTTMAPK1 | |
| SCHEMBL8031895 | 0.88 | KMT2A (0.36) | CASRKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL8031766 | 0.88 | CASR (0.40) | CASRKMT2AALDH1A1BDKRB2NPSR1 | |
| SCHEMBL8020637 | 0.88 | KMT2A (0.36) | CASRKMT2AMEN1BDKRB2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |