Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27508822 | 0.96 | CASR (0.43) | CASRALDH1A1KDM4EBDKRB2KMT2A | |
| SCHEMBL8030320 | 0.96 | CASR (0.40) | CASRALDH1A1KDM4EBDKRB2KMT2A | |
| SCHEMBL8031766 | 0.93 | CASR (0.40) | CASRALDH1A1KDM4EBDKRB2KMT2A | |
| SCHEMBL8020962 | 0.93 | CASR (0.37) | CASRALDH1A1BDKRB2KMT2ASMN1; SMN2 | |
| SCHEMBL8030013 | 0.91 | CASR (0.44) | CASRALDH1A1KDM4EBDKRB2KMT2A | |
| SCHEMBL27488060 | 0.91 | CASR (0.40) | CASRALDH1A1KDM4EBDKRB2KMT2A | |
| SCHEMBL8031966 | 0.91 | BDKRB2 (0.37) | CASRBDKRB2KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8036625 | 0.91 | CASR (0.44) | CASRALDH1A1KDM4EKMT2AMAPK1 | |
| SCHEMBL8033795 | 0.91 | ALDH1A1 (0.40) | CASRALDH1A1BDKRB2KMT2ASMN1; SMN2 | |
| SCHEMBL8020538 | 0.91 | KMT2A (0.35) | CASRBDKRB2KMT2ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | claimed |
| CN-1178523-A | Aminophenol derivatives | DIICHI PHARMACEUTICAL CO LTD (JP) | 1998-04-08 | — | — | CN | claimed |
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |
| CN-1178523-A | Aminophenol derivatives | DIICHI PHARMACEUTICAL CO LTD (JP) | 1998-04-08 | — | — | CN | disclosed |