Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2846634 | 0.87 | KDM4E (0.62) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29808854 | 0.87 | KDM4E (0.62) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL20374776 | 0.81 | RAB9A (0.64) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL231307 | 0.79 | KDM4E (0.75) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL30132720 | 0.78 | KDM4E (0.73) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL196475 | 0.78 | KDM4E (0.73) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29558566 | 0.78 | RAB9A (0.67) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5974815 | 0.78 | RAB9A (0.67) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12854008 | 0.77 | KDM4E (0.72) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL54329 | 0.77 | RAB9A (0.55) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140051-A | USE IN THE FIELD OF BIOLOGICAL ASSAYS | PROMEGA BIOSCIENCES, INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-1000042-A1 | FLUORESCENT DIBENZAZOLE DERIVATIVES AND METHODS RELATED THERETO | Promega Biosciences, Inc. (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-2000004007-A1 | FLUORESCENT DIBENZAZOLE DERIVATIVES AND METHODS RELATED THERETO | PROMEGA BIOSCIENCES, INC. (US) | 2000-01-27 | — | — | WO | disclosed |
| WO-1999003849-A1 | FLUORESCENT DIBENZAZOLE DERIVATIVES AND METHODS RELATED THERETO | PROMEGA BIOSCIENCES, INC. (US) | 1999-01-28 | — | — | WO | disclosed |