Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 14/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20622958 | 0.90 | TBXAS1 (0.49) | TBXAS1TDP1EGLN3ALDH1A1 | |
| SCHEMBL26206833 | 0.90 | TBXAS1 (0.49) | TBXAS1TDP1EGLN3ALDH1A1 | |
| SCHEMBL20623229 | 0.90 | TBXAS1 (0.49) | TBXAS1TDP1EGLN3ALDH1A1 | |
| SCHEMBL10997783 | 0.89 | EGLN3 (0.53) | TBXAS1TDP1EGLN3ALDH1A1 | |
| SCHEMBL22117141 | 0.88 | EGLN3 (0.42) | TBXAS1TDP1EGLN3ALDH1A1 | |
| SCHEMBL11463256 | 0.84 | EGLN3 (0.45) | TBXAS1TDP1EGLN3ALDH1A1 | |
| SCHEMBL11598612 | 0.84 | TBXAS1 (0.40) | TBXAS1TDP1EGLN3ALDH1A1 | |
| SCHEMBL4780723 | 0.84 | TBXAS1 (0.40) | TBXAS1TDP1EGLN3ALDH1A1 | |
| SCHEMBL5966061 | 0.84 | TBXAS1 (0.44) | TBXAS1TDP1 | |
| SCHEMBL5580017 | 0.82 | TBXAS1 (0.47) | TBXAS1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0992513-A2 | Isolated metallopeptide: compositions and synthetic methods | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-04-12 | — | — | EP | disclosed |
| EP-0552284-B1 | ISOLATED METALLOPOLYPEPTIDE: COMPOSITIONS AND SYNTHETIC METHODS | SCRIPPS RESEARCH INST (US) | 2000-03-29 | — | — | EP | disclosed |
| US-5408036-A | A polyvalent ion covalently linked to 2 to 8 polypeptide binding ligands, each of which covalently bonded to a linear polypeptide | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-04-18 | — | — | US | disclosed |
| WO-1992006110-A1 | ISOLATED METALLOPOLYPEPTIDE: COMPOSITIONS AND SYNTHETIC METHODS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1992-04-16 | — | — | WO | disclosed |