Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.58 |
| ▸ | F10 | P00742 | 4/20 | 0.58 |
| ▸ | PLG | P00747 | 3/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.58 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.58 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8016519 | 0.88 | F2 (0.55) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7415075 | 0.86 | F2 (0.74) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL8031432 | 0.84 | F2 (0.79) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8026423 | 0.84 | F2 (0.78) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL8027187 | 0.81 | F2 (0.41) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7415072 | 0.80 | F2 (0.48) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL8016597 | 0.80 | F2 (0.46) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL8016596 | 0.80 | F2 (0.45) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL8028430 | 0.78 | CNR2 (0.57) | F2RORCACSL1CNR2BCHE | |
| SCHEMBL8016601 | 0.78 | F2 (0.46) | F2F10PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |