Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CHAT | P28329 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | FUT8 | Q9BYC5 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019327 | 0.95 | TSHR (0.43) | HPGDSTSHRCHATUSP2APEX1 | |
| SCHEMBL11201158 | 0.91 | HPGDS (0.47) | HPGDSTSHRCHATUSP2APEX1 | |
| SCHEMBL8418569 | 0.88 | HPGDS (0.44) | HPGDSTSHRCHATUSP2APEX1 | |
| SCHEMBL30268659 | 0.84 | CHAT (0.52) | HPGDSTSHRCHATUSP2APEX1 | |
| SCHEMBL114494 | 0.84 | CHAT (0.52) | HPGDSTSHRCHATUSP2APEX1 | |
| SCHEMBL4104068 | 0.84 | CA12 (0.47) | HPGDSTSHRCHATUSP2APEX1 | |
| SCHEMBL11873541 | 0.83 | TSHR (0.44) | HPGDSTSHRCHATUSP2APEX1 | |
| SCHEMBL11204629 | 0.83 | HPGDS (0.46) | HPGDSTSHRCHATUSP2APEX1 | |
| SCHEMBL9010675 | 0.83 | GAA (0.48) | HPGDSTSHRCHATUSP2APEX1 | |
| SCHEMBL9803462 | 0.82 | HPGDS (0.39) | HPGDSTSHRCHATUSP2APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584045-B1 | Fiber-reactive dyes, their preparation and application | CIBA SC HOLDING AG (CH) | 2000-03-01 | — | — | EP | disclosed |
| US-5410041-A | Bisreactive dyes having a disulfophenylene bridging member | CIBA GEIGY CORPORATION (US) | 1995-04-25 | — | — | US | disclosed |
| EP-0584045-A1 | Fiber-reactive dyes, their preparation and application | CIBA-GEIGY AG (CH) | 1994-02-23 | — | — | EP | disclosed |