Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 12/20 | 0.58 |
| ▸ | CXCR1 | P25024 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032395 | 0.94 | CXCR2 (0.56) | CXCR2CXCR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8034418 | 0.80 | CXCR2 (0.66) | CXCR2CXCR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8022669 | 0.79 | CXCR2 (0.65) | CXCR2CXCR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8032068 | 0.79 | CXCR2 (0.65) | CXCR2CXCR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8022706 | 0.78 | CXCR2 (0.66) | CXCR2CXCR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL3705632 | 0.75 | CXCR2 (1.00) | CXCR2CXCR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6824309 | 0.75 | CXCR2 (1.00) | CXCR2CXCR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL5499098 | 0.75 | CXCR2 (0.76) | CXCR2CXCR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8032367 | 0.72 | CXCR2 (0.49) | CXCR2CXCR1ALDH1A1 | |
| SCHEMBL8031958 | 0.72 | CXCR2 (0.35) | CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000072800-A2 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-12-07 | — | — | WO | disclosed |