Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 11/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032400 | 0.94 | CXCR2 (0.47) | CXCR2CXCR1ALDH1A1SIGMAR1 | |
| SCHEMBL8031959 | 0.89 | CXCR2 (0.50) | CXCR2CXCR1ALDH1A1SIGMAR1NOS3 | |
| SCHEMBL8034421 | 0.86 | CXCR2 (0.52) | CXCR2CXCR1ALDH1A1SIGMAR1NOS3 | |
| SCHEMBL8022670 | 0.83 | CXCR2 (0.51) | CXCR2CXCR1ALDH1A1 | |
| SCHEMBL8032074 | 0.83 | CXCR2 (0.51) | CXCR2CXCR1ALDH1A1SIGMAR1 | |
| SCHEMBL8022708 | 0.82 | CXCR2 (0.52) | CXCR2CXCR1ALDH1A1 | |
| SCHEMBL6817701 | 0.75 | CXCR2 (0.56) | CXCR2CXCR1 | |
| SCHEMBL7212596 | 0.74 | CXCR2 (0.52) | CXCR2CXCR1 | |
| SCHEMBL8032363 | 0.72 | CXCR2 (0.58) | CXCR2CXCR1ALDH1A1 | |
| SCHEMBL7212626 | 0.72 | CXCR2 (0.47) | CXCR2CXCR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000072800-A2 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-12-07 | — | — | WO | disclosed |