Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PABPC1 | P11940 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954855 | 0.83 | KMT2A (0.56) | KMT2AMEN1KDM4EMAPTRAB9A | |
| SCHEMBL6954710 | 0.79 | KMT2A (0.49) | KMT2AMEN1KDM4EMAPTRAB9A | |
| SCHEMBL10482836 | 0.78 | KMT2A (0.51) | KMT2AMEN1KDM4EMAPTRAB9A | |
| SCHEMBL10417850 | 0.77 | KMT2A (0.58) | KMT2AMEN1KDM4EMAPTRAB9A | |
| SCHEMBL6846376 | 0.77 | KMT2A (0.58) | KMT2AMEN1KDM4EMAPTRAB9A | |
| SCHEMBL31129249 | 0.77 | KMT2A (0.67) | KMT2AMEN1KDM4EMAPTRAB9A | |
| SCHEMBL50309 | 0.77 | KMT2A (0.67) | KMT2AMEN1KDM4EMAPTRAB9A | |
| SCHEMBL10404298 | 0.77 | KMT2A (0.67) | KMT2AMEN1KDM4EMAPTRAB9A | |
| SCHEMBL3761569 | 0.77 | KMT2A (0.68) | KMT2AMEN1KDM4EMAPTRAB9A | |
| SCHEMBL4678745 | 0.76 | KDM4E (0.52) | KMT2AMEN1KDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984938-A1 | CYANOGUANIDINES AS CELL PROLIFERATION INHIBITORS | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 2000-03-15 | — | — | EP | disclosed |
| EP-0984936-A1 | CYANOGUANIDINES AS CELL PROLIFERATION INHIBITORS | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054141-A1 | CYANOGUANIDINES AS CELL PROLIFERATION INHIBITORS | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1998-12-03 | — | — | WO | disclosed |
| WO-1998054144-A1 | CYANOGUANIDINES AS CELL PROLIFERATION INHIBITORS | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1998-12-03 | — | — | WO | disclosed |