Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7135404 | 0.86 | HRH3 (0.39) | ALDH1A1KDM4EHRH3ACHE | |
| SCHEMBL8526131 | 0.86 | HRH3 (0.39) | ALDH1A1KDM4EHRH3ACHE | |
| SCHEMBL10154862 | 0.84 | HRH3 (0.37) | ALDH1A1MAPTKDM4ESMN1; SMN2GAA | |
| SCHEMBL10154855 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4ESMN1; SMN2GAA | |
| SCHEMBL10154856 | 0.82 | CHRM2 (0.43) | ALDH1A1MAPTKDM4ESMN1; SMN2GAA | |
| SCHEMBL11843722 | 0.82 | HTR2B (0.38) | ALDH1A1MAPTKDM4ESMN1; SMN2GAA | |
| SCHEMBL12882152 | 0.81 | GAA (0.62) | ALDH1A1MAPTGAAAPOBEC3AAPOBEC3G | |
| SCHEMBL10128040 | 0.80 | GAA (0.56) | ALDH1A1MAPTKDM4ESMN1; SMN2GAA | |
| SCHEMBL8036541 | 0.80 | GAA (0.56) | ALDH1A1MAPTKDM4ESMN1; SMN2GAA | |
| SCHEMBL10154859 | 0.79 | GRIN2B (0.37) | ALDH1A1MAPTKDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082268-A2 | LIGANDS OF α-ADRENOCEPTORS AND OF DOPAMINE, HISTAMINE, IMIDAZOLINE AND SEROTONIN RECEPTORS AND THE USE THEREOF | ALLA CHEM, LLC (US) | 2009-07-02 | — | — | WO | disclosed |