Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | GPX4 | P36969 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17127373 | 1.00 | ALDH1A1 (0.41) | ALDH1A1PTPN1GPX4POLBKDM4E | |
| SCHEMBL18503096 | 1.00 | ALDH1A1 (0.41) | ALDH1A1PTPN1GPX4POLBKDM4E | |
| SCHEMBL9912672 | 1.00 | ALDH1A1 (0.41) | ALDH1A1PTPN1GPX4POLBKDM4E | |
| SCHEMBL16488176 | 1.00 | ALDH1A1 (0.41) | ALDH1A1PTPN1GPX4POLBKDM4E | |
| SCHEMBL22821594 | 0.90 | ALDH1A1 (0.39) | ALDH1A1PTPN1POLBCA1CA2 | |
| SCHEMBL19683217 | 0.88 | PTPN1 (0.39) | ALDH1A1PTPN1CA1CA2CA9 | |
| SCHEMBL18510006 | 0.88 | PTPN1 (0.39) | ALDH1A1PTPN1CA1CA2CA9 | |
| SCHEMBL17209107 | 0.87 | ALDH1A1 (0.39) | ALDH1A1PTPN1GPX4POLBKDM4E | |
| SCHEMBL15196180 | 0.87 | ALDH1A1 (0.39) | ALDH1A1PTPN1GPX4POLBKDM4E | |
| SCHEMBL21162944 | 0.86 | POLB (0.37) | ALDH1A1PTPN1POLBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11214736-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2022-01-04 | — | — | US | disclosed |
| US-10934487-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2021-03-02 | — | — | US | disclosed |
| EP-3663378-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2020-06-10 | — | — | EP | disclosed |
| US-10669484-B2 | Process of preparing a light modulation element | MERCK PATENT GMBH (DE) | 2020-06-02 | — | — | US | disclosed |
| EP-3215892-B1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2020-03-18 | — | — | EP | disclosed |
| US-10550327-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2020-02-04 | — | — | US | disclosed |
| EP-2883934-B1 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2019-11-13 | — | — | EP | disclosed |
| US-10472569-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2019-11-12 | — | — | US | disclosed |
| EP-3174955-B1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2019-10-23 | — | — | EP | disclosed |
| US-10351771-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2019-07-16 | — | — | US | disclosed |
| US-20120069289-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-03-22 | — | — | US | disclosed |
| WO-2011160765-A1 | POLYMERIZIBLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2011-12-29 | — | — | WO | disclosed |
| WO-2011160764-A1 | POLYMERIZABLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2011-12-29 | — | — | WO | disclosed |
| WO-2011137956-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2011-11-10 | — | — | WO | disclosed |
| US-20110261311-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-10-27 | — | — | US | disclosed |
| US-20110261311-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-10-27 | — | — | US | disclosed |
| WO-2011110287-A1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2011-09-15 | — | — | WO | disclosed |
| WO-2011050893-A1 | POLYMERIZABLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2011-05-05 | — | — | WO | disclosed |
| US-20100272925-A1 | LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT (DE) | 2010-10-28 | — | — | US | disclosed |
| EP-2243812-A2 | Liquid crystal display | Merck Patent GmbH (DE) | 2010-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100272925-A1 | LIQUID-CRYSTAL DISPLAY | KLK3, BPHL, LPXN | ALDH1A1 2575/4885PTPN1 463/4885GPX4 3350/4885 |
| US-20110261311-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS | LPXN, MAP1LC3C, VCL | ALDH1A1 4144/4885PTPN1 1018/4885GPX4 2282/4885 |
| US-20120069289-A1 | LIQUID CRYSTAL DISPLAY | LPXN, VCL, ACP3 | ALDH1A1 3543/4885PTPN1 556/4885GPX4 2057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.