Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4000202 | 0.93 | HCAR3 (0.54) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL24900061 | 0.91 | HPGD (0.45) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL28935443 | 0.91 | HPGD (0.45) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL25734415 | 0.91 | HPGD (0.45) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL22382539 | 0.91 | MAPT (0.63) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL4280959 | 0.89 | KMT2A (0.56) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL3762305 | 0.85 | HPGD (0.58) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL29052814 | 0.84 | HCAR3 (0.69) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL29052815 | 0.84 | HCAR3 (0.69) | HCAR3KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL30537052 | 0.84 | HCAR3 (0.69) | HCAR3KMT2AMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |