Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ATP4A | P20648 | 5/20 | 0.54 |
| ▸ | ATP4B | P51164 | 5/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24157673 | 0.87 | CYP1A2 (0.56) | RAB9AMEN1KMT2AMAPTHTT | |
| SCHEMBL825345 | 0.85 | MEN1 (0.66) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL825346 | 0.85 | MEN1 (0.66) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL13936229 | 0.85 | ATP4A (0.66) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL6493241 | 0.84 | MEN1 (0.70) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL6493243 | 0.84 | MEN1 (0.70) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL8031699 | 0.83 | MAPT (0.49) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL6115945 | 0.82 | ATP4A (0.49) | RAB9AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6115942 | 0.82 | ATP4A (0.49) | RAB9AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12545463 | 0.80 | CYP1A2 (0.59) | RAB9AMEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140051-A | USE IN THE FIELD OF BIOLOGICAL ASSAYS | PROMEGA BIOSCIENCES, INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-1000042-A1 | FLUORESCENT DIBENZAZOLE DERIVATIVES AND METHODS RELATED THERETO | Promega Biosciences, Inc. (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-2000004007-A1 | FLUORESCENT DIBENZAZOLE DERIVATIVES AND METHODS RELATED THERETO | PROMEGA BIOSCIENCES, INC. (US) | 2000-01-27 | — | — | WO | disclosed |
| WO-1999003849-A1 | FLUORESCENT DIBENZAZOLE DERIVATIVES AND METHODS RELATED THERETO | PROMEGA BIOSCIENCES, INC. (US) | 1999-01-28 | — | — | WO | disclosed |