Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2603300 | 0.86 | CHRNB2 (0.53) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL12609020 | 0.86 | CHRNB2 (0.53) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL22213795 | 0.86 | CHRNB2 (0.53) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL2603292 | 0.85 | CHRNB2 (0.51) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL28814955 | 0.83 | CHRNB2 (0.50) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL4420298 | 0.83 | KDM4E (0.49) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL11509425 | 0.82 | SCN3A (0.48) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL17130333 | 0.82 | CHRNB2 (0.49) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL18729770 | 0.82 | CHRNB2 (0.49) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL18751620 | 0.82 | CHRNB2 (0.49) | CHRNB2CHRNA7CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609010-B1 | A process for producing a diolefin polymer or copolymer and a rubber composition containing such a diolefin polymer or copolymer | BRIDGESTONE CORP (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-5527860-A | PROMOTER IS REACTION PRODUCT OF A SECONDARY AMINE AND ORGANOLITHIUM COMPOUND OR ALCOHOL AND A LITHIUM ALKOXIDE | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0609010-A2 | A process for producing a diolefin polymer or copolymer and a rubber composition containing such a diolefin polymer or copolymer | BRIDGESTONE CORPORATION (JP) | 1994-08-03 | — | — | EP | disclosed |