Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30610439 | 0.89 | NPSR1 (0.47) | PTPN1MEN1TSHRKMT2ANPSR1 | |
| SCHEMBL28050368 | 0.86 | NPC1 (0.45) | PTPN1MEN1TSHRKMT2ANPSR1 | |
| SCHEMBL8485416 | 0.86 | PTPN1 (0.48) | PTPN1NPSR1ALDH1A1ALOX15CA12 | |
| SCHEMBL27617215 | 0.84 | AKR1C3 (0.47) | PTPN1MEN1TSHRKMT2ANPSR1 | |
| SCHEMBL9068711 | 0.83 | PTPN1 (0.49) | PTPN1NPSR1ALDH1A1ALOX15CA12 | |
| SCHEMBL27617112 | 0.83 | NPSR1 (0.41) | PTPN1MEN1TSHRKMT2ANPSR1 | |
| SCHEMBL28609649 | 0.83 | GAA (0.46) | PTPN1MEN1TSHRKMT2ANPSR1 | |
| SCHEMBL28605602 | 0.82 | PTPN1 (0.51) | PTPN1MEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL8044308 | 0.82 | PTPN1 (0.45) | PTPN1MEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL6438589 | 0.81 | PTPN1 (0.49) | PTPN1KMT2ANPSR1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248399-A | O-amino aromatic amide derivative and preparation method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2021-08-13 | — | — | CN | disclosed |
| CN-111630154-A | Enhancing fibroblast regenerative activity | 菲格内有限责任公司 | 2020-09-04 | — | — | CN | disclosed |
| WO-2000066751-A1 | EXPRESSION CASSETTE FOR EFFICIENT PRODUCTION OF A PROTEIN | DSM N.V. (NL) | 2000-11-09 | — | — | WO | disclosed |