Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2933449 | 1.00 | EPHX1 (0.44) | EPHX1ALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL8028436 | 1.00 | EPHX1 (0.44) | EPHX1ALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL2619933 | 1.00 | EPHX1 (0.44) | EPHX1ALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL2619928 | 1.00 | EPHX1 (0.44) | EPHX1ALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL2631667 | 0.87 | EPHX1 (0.43) | EPHX1ALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL2109375 | 0.87 | EPHX1 (0.43) | EPHX1ALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL2109377 | 0.87 | EPHX1 (0.43) | EPHX1ALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL3772199 | 0.86 | EPHX1 (0.40) | EPHX1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL3772201 | 0.86 | EPHX1 (0.40) | EPHX1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8039248 | 0.86 | EPHX1 (0.40) | EPHX1ALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009091016-A1 | CONDENSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-07-23 | — | — | WO | disclosed |