Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030379 | 1.00 | EPHX1 (0.40) | EPHX1ALDH1A1ALOX12LMNAKMT2A | |
| SCHEMBL3772199 | 1.00 | EPHX1 (0.40) | EPHX1ALDH1A1ALOX12LMNAKMT2A | |
| SCHEMBL3772201 | 1.00 | EPHX1 (0.40) | EPHX1ALDH1A1ALOX12LMNAKMT2A | |
| SCHEMBL2619950 | 1.00 | EPHX1 (0.40) | EPHX1ALDH1A1ALOX12LMNAKMT2A | |
| SCHEMBL8028436 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1ALOX12LMNAKMT2A | |
| SCHEMBL2619933 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1ALOX12LMNAKMT2A | |
| SCHEMBL8034256 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1ALOX12LMNAKMT2A | |
| SCHEMBL2933449 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1ALOX12LMNAKMT2A | |
| SCHEMBL2619928 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1ALOX12LMNAKMT2A | |
| SCHEMBL2109591 | 0.85 | EPHX1 (0.41) | EPHX1ALDH1A1ALOX12LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009091016-A1 | CONDENSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-07-23 | — | — | WO | disclosed |