Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.82 |
| ▸ | ATM | Q13315 | 1/20 | 0.73 |
| ▸ | DRD2 | P14416 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 3/20 | 0.56 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352566 | 0.83 | MEN1 (0.86) | MEN1KMT2AATMDRD2MAPK1 | |
| SCHEMBL8304330 | 0.80 | DRD2 (0.78) | MEN1KMT2AATMDRD2MAPK1 | |
| SCHEMBL9001267 | 0.79 | DRD2 (0.76) | MEN1KMT2AATMDRD2MAPK1 | |
| SCHEMBL6505862 | 0.79 | DRD2 (0.71) | MEN1KMT2AATMDRD2MAPK1 | |
| SCHEMBL5669693 | 0.78 | KMT2A (0.76) | MEN1KMT2AATMDRD2MAPK1 | |
| SCHEMBL12897535 | 0.77 | DRD2 (0.69) | MEN1KMT2AATMDRD2MAPK1 | |
| SCHEMBL19773023 | 0.77 | DRD2 (1.00) | MEN1KMT2AATMDRD2DRD4 | |
| SCHEMBL6906362 | 0.77 | MEN1 (0.75) | MEN1KMT2AATMDRD2MAPK1 | |
| SCHEMBL5245576 | 0.76 | MEN1 (0.74) | MEN1KMT2AATMDRD2MAPK1 | |
| SCHEMBL4747037 | 0.76 | DRD2 (0.76) | MEN1KMT2AATMDRD2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099177-A1 | AMINO IMIDAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-08-13 | — | — | WO | disclosed |