Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.35 |
| ▸ | PDE2A | O00408 | 5/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.32 |
| ▸ | STK3 | Q13188 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034044 | 0.88 | GRM2 (0.41) | EPHX2PDE2AGPR88KDM1ARCOR1 | |
| SCHEMBL8052175 | 0.88 | EPHX2 (0.39) | EPHX2PDE2AGRM2 | |
| SCHEMBL8045198 | 0.87 | JAK2 (0.36) | EPHX2PDE2AGPR88SCN10AJAK2 | |
| SCHEMBL16579012 | 0.87 | CYP2C9 (0.38) | PDE2AKDM1ARCOR1MMP12L3MBTL1 | |
| SCHEMBL8045439 | 0.87 | L3MBTL1 (0.40) | EPHX2PDE2AGPR88SCN10AKDM1A | |
| SCHEMBL8052426 | 0.86 | CHRM4 (0.35) | EPHX2PDE2AGPR88SCN10AMMP12 | |
| SCHEMBL8046242 | 0.86 | — | — | |
| SCHEMBL8052400 | 0.86 | HTR2C (0.35) | EPHX2PDE2AGPR88RPS6KB1 | |
| SCHEMBL16579011 | 0.85 | KDM1A (0.37) | PDE2ASCN10AKDM1ARCOR1JAK2 | |
| SCHEMBL8049143 | 0.85 | EPHX2 (0.38) | EPHX2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733692-B1 | Liquid crystalline compound, liquid crystal composition containing the same, and display device | CHISSO CORP (JP) | 2000-06-14 | — | — | EP | disclosed |
| US-5714088-A | TRIFLUOROMETHYL- OR -METHOXYPHENYL-SUBSTITUTED BRANCHED ALKYL-SUBSTITUTED CYCLOHEXANES; LARGE POSITIVE VALUE OF DIELECTRIC ANISOTROPY; VERY LOW VISCOSITY; HIGH VOLTAGE HOLDING RATIO(SPECIFIC RESISTANCE); UV STABILITY | CHISSO CORPORATION (JP) | 1998-02-03 | — | — | US | disclosed |
| EP-0733692-A1 | Liquid crystalline compound, liquid crystal composition containing the same, and display device | Chisso Corporation (JP) | 1996-09-25 | — | — | EP | disclosed |