Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | SHBG | P04278 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | STS | P08842 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13049833 | 1.00 | ESR1 (0.53) | ESR1ESR2CYP19A1SHBGDRD2 | |
| SCHEMBL30835166 | 0.89 | ESR1 (0.55) | ESR1ESR2CYP19A1SHBGHSD17B10 | |
| SCHEMBL12401916 | 0.89 | ESR1 (0.55) | ESR1ESR2CYP19A1SHBGHSD17B10 | |
| SCHEMBL16527048 | 0.87 | ESR1 (0.58) | ESR1ESR2CYP19A1SHBGHSD17B10 | |
| SCHEMBL683191 | 0.81 | ESR1 (0.50) | ESR1ESR2CYP19A1SHBGDRD2 | |
| SCHEMBL12332825 | 0.80 | HTR2C (0.62) | SLC6A4HTR2B | |
| SCHEMBL13948529 | 0.80 | HTR2C (0.62) | SLC6A4HTR2B | |
| SCHEMBL8287030 | 0.78 | CYP26A1 (0.44) | ESR1ESR2DRD2DRD3DRD4 | |
| SCHEMBL30298331 | 0.78 | SRD5A1 (0.47) | DRD2CYP3A4SLC6A4HTR2BSLC6A3 | |
| SCHEMBL413401 | 0.78 | SRD5A1 (0.47) | DRD2CYP3A4SLC6A4HTR2BSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993429-A1 | METHOD FOR PRODUCING AND PURIFYING 3-(4-HYDROXYPHENYL)-1,1,3-TRIMETHYLINDAN-5-OL | BAYER AG (DE) | 2000-04-19 | — | — | EP | claimed |
| WO-1999001413-A1 | METHOD FOR PRODUCING AND PURIFYING 3-(4-HYDROXYPHENYL)-1,1,3-TRIMETHYLINDAN-5-OL | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-14 | — | — | WO | claimed |
| US-4254056-A | ANTIINFLAMMATORY AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |