SCHEMBL30298331

SCHEMBL30298331

Cc1ccc2c(c1)CCC2C

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 5/20 0.47
SLC6A4 P31645 2/20 0.42
ACHE P22303 1/20 0.39
DRD2 P14416 1/20 0.39
DRD1 P21728 1/20 0.39
HTR2C P28335 2/20 0.39
HTR2A P28223 1/20 0.39
HTR2B P41595 1/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A3 Q01959 1/20 0.38
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNA4 P43681 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL413401 1.00 SRD5A1 (0.47) SRD5A1SLC6A4ACHEDRD2DRD1
SCHEMBL6902991 0.88 SRD5A1 (0.42) SRD5A1SLC6A4ACHEHTR2CHTR2A
SCHEMBL409985 0.83 ACHE (0.43) SRD5A1SLC6A4ACHEDRD2DRD1
SCHEMBL30298336 0.83 ACHE (0.43) SRD5A1SLC6A4ACHEDRD2DRD1
SCHEMBL18045112 0.78 ACHE (0.50) SRD5A1SLC6A4ACHEHTR2CSLC6A2
SCHEMBL23592008 0.78 SRD5A1 (0.49) SRD5A1HTR2CHTR2AHTR2B
SCHEMBL12548674 0.78 DRD2 (0.41) DRD2DRD1HTR2CHTR2AHTR2B
SCHEMBL12548151 0.78 DRD2 (0.41) DRD2DRD1HTR2CHTR2AHTR2B
SCHEMBL13948529 0.78 HTR2C (0.62) SRD5A1SLC6A4HTR2CHTR2AHTR2B
SCHEMBL13948755 0.78 SRD5A1 (0.49) SRD5A1SLC6A4ACHEHTR2CHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115768740-A Process for preparing indene acrolein derivative 弗门尼舍有限公司 2023-03-07 CN disclosed