SCHEMBL8034566

SCHEMBL8034566

C=CCCC1CCC(C2CCC(c3ccc(C)cc3)CC2)CC1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 9/20 0.41
CYP2C9 P11712 3/20 0.38
ALDH1A1 P00352 2/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
MAPK1 P28482 1/20 0.37
KMT2A Q03164 1/20 0.37
ESR1 P03372 6/20 0.36
CYP3A4 P08684 2/20 0.36
SLC18A3 Q16572 1/20 0.33
DGAT1 O75907 3/20 0.33
SOAT1 P35610 1/20 0.33
CYP2D6 P10635 1/20 0.33
TP53 P04637 1/20 0.31
ATM Q13315 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAP1LC3B Q9GZQ8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9482374 1.00 ESR2 (0.41) ESR2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL9482361 1.00 ESR2 (0.41) ESR2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL6141684 0.92 FFAR1 (0.37) ESR2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL8530566 0.90 ESR2 (0.38) ESR2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL8530569 0.90 ESR2 (0.38) ESR2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL8530563 0.90 ESR2 (0.38) ESR2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL27475792 0.88 ALDH1A1 (0.35) ESR2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL6459259 0.87 ESR2 (0.32) ESR2CYP2C9LMNAESR1CYP3A4
SCHEMBL6142053 0.87 FFAR1 (0.40) ESR2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL6459255 0.87 ESR2 (0.32) ESR2CYP2C9LMNAESR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4514919-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS Merck Patent GmbH (DE) 2025-03-05 EP disclosed
EP-4514920-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2025-03-05 EP disclosed
EP-4511446-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2025-02-26 EP disclosed
EP-3553154-B1 LIQUID CRYSTAL COMPOSITE AND LIQUID CRYSTAL DIMMER ELEMENT JNC CORP (JP) 2025-02-12 EP disclosed
WO-2023208801-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS MERCK PATENT GMBH (DE) 2023-11-02 WO disclosed
WO-2023209049-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-11-02 WO disclosed
WO-2023203043-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-10-26 WO disclosed
US-20230333428-A1 LIQUID CRYSTAL DISPLAY DEVICE Sharp Display Technology Corporation (JP) 2023-10-19 US disclosed
EP-4247914-A1 LIQUID CRYSTAL MEDIUM Merck Patent GmbH (DE) 2023-09-27 EP disclosed
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-9637684-B2 Composition and liquid crystal display element using same DIC CORPORATION (JP) 2017-05-02 US disclosed
US-9580654-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-02-28 US disclosed
US-20170015906-A1 LIQUID CRYSTAL COMPOSITION SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO, LTD. (CN) 2017-01-19 US disclosed
EP-0805134-B1 NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION CHISSO CORP (JP) 2000-08-30 EP disclosed
EP-0733692-B1 Liquid crystalline compound, liquid crystal composition containing the same, and display device CHISSO CORP (JP) 2000-06-14 EP disclosed
US-5714088-A TRIFLUOROMETHYL- OR -METHOXYPHENYL-SUBSTITUTED BRANCHED ALKYL-SUBSTITUTED CYCLOHEXANES; LARGE POSITIVE VALUE OF DIELECTRIC ANISOTROPY; VERY LOW VISCOSITY; HIGH VOLTAGE HOLDING RATIO(SPECIFIC RESISTANCE); UV STABILITY CHISSO CORPORATION (JP) 1998-02-03 US disclosed
EP-0805134-A1 NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-11-05 EP disclosed
CN-1140194-A Liquid crystalline compound having branched alkyl group at its side chain and liquid crystal composition containing the same CHISSO CORP (JP) 1997-01-15 CN disclosed
EP-0733692-A1 Liquid crystalline compound, liquid crystal composition containing the same, and display device Chisso Corporation (JP) 1996-09-25 EP disclosed
US-5185098-A Liquid crystalline mixtures containing 3,4-difluorophenyl-substituted bicyclohexyls HOFFMANN-LA ROCHE INC. (US) 1993-02-09 US disclosed