SCHEMBL803458

SCHEMBL803458

COc1ccc(-c2ccc(C3CCC(C4CCC(C)CC4)CC3)c(F)c2F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 10/20 0.34
FEN1 P39748 10/20 0.34
FPR2 P25090 4/20 0.34
USP30 Q70CQ3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13868125 1.00 ALOX5AP (0.34) ALOX5APFEN1FPR2USP30
SCHEMBL10035142 0.96 ALOX5AP (0.36) ALOX5APFEN1FPR2USP30
SCHEMBL16922997 0.96 ALOX5AP (0.36) ALOX5APFEN1FPR2USP30
SCHEMBL172469 0.94 HTR2C (0.34) ALOX5APFEN1USP30
SCHEMBL13000031 0.93 ALOX5AP (0.39) ALOX5APFEN1FPR2
SCHEMBL170527 0.90 HTR2C (0.37) ALOX5APFEN1USP30
SCHEMBL12999898 0.89 ALOX5AP (0.41) ALOX5APFEN1FPR2
SCHEMBL19754822 0.83 ESR2 (0.38) ALOX5APFEN1
SCHEMBL12437063 0.83 ESR2 (0.38) ALOX5APFEN1
SCHEMBL172422 0.83 ESR2 (0.38) ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-11788009-B2 Liquid-crystalline medium for use in a switching element MERCK PATENT GMBH (DE) 2023-10-17 US disclosed
US-11762241-B2 Device for the regulation of light transmission MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
US-11760931-B2 Liquid-crystalline medium for use in a switching element MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
US-11702597-B2 Azo dye MERCK PATENT GMBH (DE) 2023-07-18 US disclosed
US-20180195003-A1 PROCESS FOR THE STABILISATION OF LIQUID CRYSTAL MEDIA MERCK PATENT GMBH (DE) 2018-07-12 US disclosed
US-9944416-B2 Filling device and use thereof for dispensing a fluid MERCK PATENT GMBH (DE) 2018-04-17 US disclosed
US-9938229-B2 Polymerisable compounds and the use thereof in liquid-crystal displays MERCK PATENT GMBH (DE) 2018-04-10 US disclosed
US-9926490-B2 Liquid crystal medium MERCK PATENT GMBH (DE) 2018-03-27 US disclosed
US-20180057743-A1 LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2018-03-01 US disclosed
US-7440160-B2 Electro-optical light modulating element, electro-optical display and modulating medium MERCK PATENT GMBH (DE) 2008-10-21 US disclosed
US-7425355-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2008-09-16 US disclosed
US-20080197319-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT (DE) 2008-08-21 US disclosed
US-20080191166-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT (DE) 2008-08-14 US disclosed
US-20080193681-A1 Liquid-Crystal Medium MERCK PATENT GMBH (DE) 2008-08-14 US disclosed
US-20080191167-A1 Liquid-crystalline medium MERCK PATENT GMBH 2008-08-14 US disclosed
US-7371437-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2008-05-13 US disclosed
US-7335403-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2008-02-26 US disclosed
US-20070080324-A1 mixture of polar compounds of negative dielectric anisotropy; electro-optical display with active-matrix addressing based on the ECB(electrically controlled birefringence), PALC (positive charge assisted leakage current) or IPS ( in plane switching) effect MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
US-20070051920-A1 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2007-03-08 US disclosed